A home off the Edgartown-Vineyard Haven Road was completely destroyed by fire early Friday morning. No one was injured, Tisbury fire chief John Schilling said.

Mr. Schilling said the call came in at 4:20 a.m. Friday for the fire at 59 Edgartown Road. When volunteer firefighters arrived, the chief said flames were coming through the roof of the house, an older single-family home set back from the road on an elevated lot heavily overgrown with vegetation. The only occupant of the house was the owner who had called in the fire, and was outside the home when firefighters arrived.

The homeowner, whose name had not been released yet, was transported to the Martha’s Vineyard Hospital, although the owner was not injured in the fire. “We have not had a chance to talk to the homeowner, we do not know his condition or the reason for transport,” the chief said.

All Tisbury firefighters responded to the scene, as well as Tisbury EMS. Oak Bluffs firefighters and EMS were called in on mutual aid, first to cover the Tisbury station and later to assist at the scene of the fire.

Approximately 40 first responders were on the scene, the chief said.

Response was hampered by limited access to the house and the fact that a primary power line had burned through and fallen across the sole access point when firefighters arrived, the chief said. He said firefighters had to wait for nearly an hour until Nstar crews arrived on the scene to shut off the power.

“It would not have changed the outcome, but was another element of risk,” the chief said.

He said the house was a total loss. An investigation has begun into the cause of the fire.