For the second time in three months, the sign at Lambert’s Cove Inn in West Tisbury was stolen sometime Saturday night or Sunday morning. Police said they are searching for suspects in a string of sign-related heists in recent months.

The previous sign at the Lambert’s Cove Inn was stolen in February, and the sign in front of the Focus Christian fellowship center down the road has also been stolen several times over the past year.

An “Open for Dinner” sign that hung below the main sign at the end of the inn road and a street sign were also stolen over the weekend.

Scott Jones, co-owner of the inn, said the previous wooden sign, handmade with engraved lettering, was valued at $3,500. That sign was stolen on Feb. 10, about six weeks after a motorist knocked down the previous sign.

Mr. Jones said he and his partner Kell Hicklin purchased a plastic sign this time with vinyl letters, valued at about $1,500. They secured the sign to the post with several padlocks. But this did not deter the unknown thieves, who apparently used bolt cutters to remove the sign from the post.

“It seems pretty clear this was premeditated . . . when we put the locks up, it seemed whoever did this took it as a challenge,” Mr. Jones said.

He said the sign was last seen around 9:30 p.m. Saturday by an employee, and was discovered missing early Sunday morning. The last time the sign was stolen, the inn owners offered a reward of $200 for its return, no questions asked. This time they are offering a $300 reward for information leading to the arrest of those involved.

“It’s not just the expense, it’s the customers we lose because the sign isn’t there. Every day four or six people drive by that sign and decide to pay us a visit, and now they drive by and don’t even know we’re there,” he said.

Anyone with information about the incident is asked to call the West Tisbury police at 508-693-0020.