Regina Brenner of Crest avenue, Winthrop, died unexpectedly at the Massachusetts General Hospital in Boston on March 21. She was 50 years old.

Born in Oak Bluffs, she was the beloved daughter of the late Jean Chapman and Louis Trebby. She was raised on Martha’s Vineyard, later moving to Winthrop where she has resided for the past 23 years. For the past 10 years she was employed with WGBH as a Unit Manager. Very active in community affairs, she was a member of the Winthrop Yacht Club, Winthrop High School PTO and the Winthrop Improvement and Historical Society. She was most active with St. John’s Episcopal Church in Winthrop, where she was a member of the altar guild, the liturgical committee, the choir, the Episcopal Church Women, as well as a past member of the Vestry. Regina also served as a sub-deacon of the parish.

She was the beloved wife of 21 years to Lawrence (Larry) Brenner and the loving mother of Samuel Brenner of Winthrop. She is survived by her siblings Bettina Trebby-Preston of Hillsborough, N.H., Maria Trebby of Nantucket, Carla Metell of Melrose, Robert Trebby of Charlestown, Julia Fernandez of Gilbert, Ariz., and Thomas Trebby of Vineyard Haven.

The funeral was conducted in Winthrop on Thursday, March 26, followed by funeral services in the St. John Episcopal Church. Committal was private.

Memorial donations may be made to either the St. John’s Episcopal Church 222 Bowdoin St., Winthrop MA 02152 or the Winthrop Public Library, 2 Metcalf Sq. Winthrop MA 02152. To sign Regina’s online guestbook go to the Web site caggianofuneralhome.com.