Regina Mary Cuddyer Policastro of Mission Hill died Nov. 13 after a brief illness. She was 68 and had been a summer resident of Chilmark.

She was a native of Jamaica Plain, attended Cathedral High School, Suffolk and Harvard Universities and numerous clinical laboratory courses.

She was a clinical laboratory supervisor at Brigham and Womans Hospital Southern Jamaica Plain Clinic for over 20 years, and had retired after 40 years in her field.

She was a devoted mother and homemaker and was dedicated to her children and their education. She was an avid reader, loved the beach and fishing with her husband and children.

She spent many summers at the Poole camp in Menemsha and eventually her own home in Chilmark. In recent years she had begun to enjoy winters in Costa Rica.

She loved to travel and visited much of the U.S. and Europe.

She was at peace watching the sunset at Menemsha or in her garden with her dog Mayday and a book by her side.

She is survived by her husband of 39 years: James C Policastro of Mission Hill; her children John Policastro of Jamaica Plain, James Policastro of Vineyard Haven, David Policastro of Somerville, and Mary Policastro of Philadelphia. She was predeceased by her parents William Henry Cuddyer and Mary Frances (McNulty) Cuddyer of Jamaica Plain. She is also survived by her brothers Thomas Cuddyer of Laguna Beach, Calif., Brian Cuddyer of San Marcos, Calif., and Paul Cuddyer of Rancho Santo Margarita, Calif., William Cuddyer of Jamaica Plain and sister Nancy Cuddyer of Jamaica Plain; and many loving, cousins, nieces and nephews, as well as many brothers and sisters in law.