Two Island men were arrested this week in connection with a nearly 10-month investigation into a large-scale drug trafficking operation by the federal Drug Enforcement Agency (DEA) and the Martha’s Vineyard Drug Task Force. The arrests led to search warrants being issued in three different states.

Sean Herrmann, 31, was arrested by a federal drug enforcement task force at his residence in East Greenbush, N.Y. last Wednesday on federal charges of drug possession and distribution, DEA special agent Erin McKenzie-Mulvey said.

Mr. Herrmann is originally from Edgartown and still spends time at his family home on Teaberry Lane.

Members of the Albany, N.Y., division of the DEA started an investigation into Mr. Herrmann’s alleged drug activities last June, according to state police Sgt. Jeff Stone, who heads the Vineyard drug task force. That investigation led to the issuance of 10 search warrants that were executed last Wednesday and Thursday in New York, Massachusetts and Connecticut.

Members of the Vineyard drug task force and DEA agents executed search warrants at both the Herrmann home on Teaberry Lane and at the home of Jonas Cavallo in Edgartown, Sergeant Stone said.

At the Herrmann home, police seized approximately 1,000 Percocet pills, eight ounces of marijuana, a handgun and around $6,000 in cash. The items were found on the person of David Herrmann, Sean Herrmann’s brother, police said.

Police also seized eight pounds of marijuana from the Cavallo home and a 2003 Toyota pickup truck, Sergeant Stone said. Mr. Cavallo was home when police searched the home, although he was not arrested or charged.

Meanwhile, DEA agents in Framingham arrested Edgartown resident Andrew Nourse, 28, on a charge of possession of marijuana with intent to distribute. The same day, police in Falmouth executed a search warrant at the residence of Adam Fender, and seized approximately eight pounds of marijuana and around $16,000 in cash.

Mr. Fender also was not arrested or charged, Sergeant Stone said.

He said the amount of illegal drugs seized here was large for the Vineyard. He estimated the street value of the Percocets at around $15,000 and the value of the marijuana seized at both locations between $40,000 or $65,000. The investigation is ongoing and may lead to more arrests, he said.